The Stott laboratory is comprised of bioengineers, biologists and chemists focused on translating technological advances to relevant applications in clinical medicine. Specifically, we are interested in using microfluidics, imaging, and biopreservation technologies to create tools that increase our understanding of cancer biology and of the metastatic process. The Stott laboratory has co-developed innovative microfluidic devices that can isolate extraordinarily rare circulating tumor cells (CTCs) and extracellular vesicles (EVs) from the blood of cancer patients. New microfluidic tools are being developed to both manipulate and interrogate these cells and vesicles at a single particle level. We also look at tumor specimens using multispectral imaging, hoping that the exploration of the spatial relationships between immune cells and tumor tissue will help us better predict treatment response. Ultimately, we hope that by working in close partnership with the clinicians and cell biologists at the Mass General Cancer Center, we can create new tools that directly impact patient care.